Pronunciation: KOE-sin-TROE-pin
Generic Name: Cosyntropin
Brand Name: Cortrosyn
Cortrosyn is used for:
Helping doctors diagnose adrenal gland problems (eg, Addison disease, adrenal insufficiency caused by steroid use, tumors). It may also be used for other conditions as determined by your doctor.
Cortrosyn is a man-made (synthetic) portion of the natural hormone corticotropin (ACTH). It works by stimulating the adrenal cortex to produce and secrete adrenocortical hormones.
Do NOT use Cortrosyn if:
- you are allergic to any ingredient in Cortrosyn
- you are using interleukin-2 (eg, aldesleukin)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Cortrosyn:
Some medical conditions may interact with Cortrosyn. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have kidney disease
Some MEDICINES MAY INTERACT with Cortrosyn. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low electrolyte (eg, potassium, sodium) levels may be increased
- Itraconazole because it may increase the risk of Cortrosyn's side effects
- Carbamazepine because it may decrease Cortrosyn's effectiveness
- Anticoagulants (eg, warfarin) because their effectiveness may be decreased and the risk of their side effects may be increased by Cortrosyn
- Interleukin-2 (eg, aldesleukin), mifepristone, quinolones (eg, levofloxacin), or ritodrine because the risk of their side effects may be increased by Cortrosyn
This may not be a complete list of all interactions that may occur. Ask your health care provider if Cortrosyn may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Cortrosyn:
Use Cortrosyn as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Cortrosyn is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Cortrosyn at home, a health care provider will teach you how to use it. Be sure you understand how to use Cortrosyn. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
- Do not use Cortrosyn if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
- Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
- If you miss a dose of Cortrosyn, contact your doctor right away.
Ask your health care provider any questions you may have about how to use Cortrosyn.
Important safety information:
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cortrosyn while you are pregnant. It is not known if Cortrosyn is found in breast milk. If you are or will be breast-feeding while you use Cortrosyn, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Cortrosyn:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Redness or swelling at the injection site.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fast, slow, or irregular heartbeat; severe or persistent headache or dizziness; swelling of the hands, ankles, or feet.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
See also: Cortrosyn side effects (in more detail)
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.
Proper storage of Cortrosyn:
Cortrosyn is usually handled and stored by a health care provider. If you are using Cortrosyn at home, store Cortrosyn as directed by your pharmacist or health care provider. Keep Cortrosyn out of the reach of children and away from pets.
General information:
- If you have any questions about Cortrosyn, please talk with your doctor, pharmacist, or other health care provider.
- Cortrosyn is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information is a summary only. It does not contain all information about Cortrosyn. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
More Cortrosyn resources
- Cortrosyn Side Effects (in more detail)
- Cortrosyn Use in Pregnancy & Breastfeeding
- Cortrosyn Drug Interactions
- Cortrosyn Support Group
- 0 Reviews for Cortrosyn - Add your own review/rating
- Cortrosyn Prescribing Information (FDA)
- Cosyntropin Prescribing Information (FDA)
Compare Cortrosyn with other medications
- Adrenocortical Insufficiency
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